RECOMB-seq was founded in 2011 as a response to the expanding applications of high-throughput sequencing as a tool of basic science and biomedicine. The conference gathered leading researchers in computational genomics and genomic biology to discuss emerging frontiers in algorithm development for sequencing data. The emphasis is on applying computational approaches to improve analysis, interpretation and data management. Since then, the scope of RECOMB-seq has expanded beyond sequencing data to include assembled data as well, all the while focusing on methodological developments. For more about our history, see our history page or our YouTube channel.